SCIENTIFIC NAME / SYNONYMS
Garcinia cambogia (Gaertn.) DESRET.
Garcinia rubber guta (L.) N. Robson
FAMILY
Perikumfamilien ( Hypericaceae).
BOTANICAL DESCRIPTION
Garcinia is a low to medium tall tree with rounded crown and shiny, dark green leaves. The oval, fleshy fruit is the size of an orange, have thin skin and deep furrows, and become yellow or red when ripe.
Prevalence
Resident in India. Grown in other countries in Southeast Asia.
Droge / Applied PLANT PARTS
Fruit shell used as a spice and medicine.
Garciniafrukt accompanied Herb List from the Norwegian Medicines Agency classified as not drug , and can be traded freely. Other parts of the plant is classified as a prescription drug .
INGREDIENTS
The contents of hydroksysitronsyre (hydroxycitric acid, abbreviated HCA) which is considered as the active ingredient through the use of Garcinia as weight-reducing agent. Moreover, the smaller amounts of citric acid.
Herb PROPERTIES AND EFFECT
Weight reduction, is used in slimming products. The drug HCA in Garcinia indicated to inhibit lipogenesis, reduce production of cholesterol and fatty acids increase the production of glycogen in the liver, curb appetite and increase the body’s production of heat. Does protective against ulcers.
MAY BE USED BY THE HEALTH PROBLEMS / DISEASES
Obesity, high cholesterol, rheumatism, stomach ailments, intestinal worms and parasites.
INTRODUCTION
Plant genus Garcinia contains about 200 species of slow-growing trees and shrubs, and is a resident of the Old World tropics, especially Asia, Polynesia and South Africa. Garcinia cambogia is one of about 30 Garcinia species found in India.
TRADITIONAL APPLICATION OF GARCINIA
The fruit of the Garcinia has long been used as a spice in India, especially along the west coast, and of the Muslim population in Laos, Malaysia, Thailand and Myanmar (formerly Burma). Although the fruits are edible, they are generally considered too acidic to be eaten raw. An extract of the dried fruit is traditionally consumed for food with lamb to improve digestion. In Sri Lanka, the fruits harvested just before they are ripe, cut into chunks, sun-dried and stored for later use. In folk tradition in India, the dried fruit peel has been boiled and used against rheumatism and stomach ailments. It activates digestion and has been used as a powerful laxative to treat intestinal worms and parasites. Garcinia has also been shown to have a protective effect against gastric ulcers.
Source of drug HCA, which affects fatty acid synthesis
In 1965, Indian scientists identified a new compound, hydroksysitronsyre (hydroxycitricacid, abbreviated HCA) as a general acid in the fruit of Garcinia cambogia . Previously, the organic acids in fruit have been identified as tartarsyre and citric acid. The dried fruit shells are HCA at concentrations up to 30%. Studies in the early 1970’s showed that HCA inhibited fatty acid synthesis in rats. Further studies revealed that HCA decreased rate of lipogenesis when given intravenously or peritoneum. Given by mouth reduced the fatty acid and cholesterol synthesis only when given before meals. This led to the assumption that if the HCA to inhibit lipogenesis, but not work on the normal energy production in the human cell’s mitochondria, it could be of value to specific lipid disorders and work against obesity. Until the early 1990’s it was published several studies on the mechanism of action of HCA when it came to fat production and metabolism in rats. The studies showed that the drug reduced fatty acid synthesis in liver and fat tissue, and produced significant reduction in food intake and decreased body weight in laboratory rats.
One has also found that Garcinia can raise levels of certain chemicals in the brain, like serotonin, which is a key regulator of appetite control. The herb will thus also have a dampening effect on appetite. Unlike other diet products, does not stimulate Garcinia central nervous system to burn more calories.
HCA AS A WEIGHT-REDUCING AGENT
Experience with the use of HCA as a weight-reducing agent in humans health is mixed. In a study from 1996 of 60 obese men and women who took the supplement for eight weeks, it seemed as if the HCA helped them to lose weight, compared with a control group that received placebo. But in a subsequent 1998 study, published in the Journal of the American Medical Association (JAMA) in which 135 obese adults took Garcinia for 12 weeks, could not show any measurable weight loss. (Participants in the study took a high fiber and low-calorie diet, and some researchers believe that the fibers interfere with the absorption of the therapeutic substance HCA). To make the confusion even greater, a study from 2000 that the supplement seemed to help women lose weight, even if not curbed the appetite.
It is not known any interactions between Garcinia and food or medications. More research is needed to determine whether a diet rich in fiber, or other nutritional factors may influence the effectiveness of HCA. It is important to remember that there is no “magic pill” for weight loss. When used as a slimming agent is Garcinia often combined with other herbs and the mineral chromium. The usual dose is the ingestion of 500 mg HCA three times daily. This is taken ½ to 1 hour before each meal with plenty of water.
WARNINGS, SIDE EFFECTS AND CONTRAINDICATIONS
Garcinia has been used continuously and safely as food for centuries, and whether or not to acute or chronic poisoning of the herb. Dietary supplements containing HCA are not known to cause side effects. Diabetic patients must exercise great caution when using Garcinia, when the herb affects blood sugar. People with Alzheimer’s disease and other dementia syndrome should avoid Garcinia because of the possibility of production of acetylcholine in the brain. As with many other supplements, are not Garcinia thoroughly tested on pregnant women. If you are pregnant or planning to become, or are nursing, you should avoid supplements with Garcinia. In Ayurvedic medicine is said to Garcinia not be used at high Vata state.
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